In a recent Reddit AMA, Ubisoft revealed some details about the Permadeath Mode in Watch Dogs Legion.
They confirmed the following :
” Permadeath is an option in the main game, so you do not have to play with Permadeath on. Either way, you can choose to use one character throughout the game – as long as they are not arrested or hospitalized (or killed), you can stick with the same character throughout – except for a couple of instances where you might need someone specific.If you are playing.
in Permadeath Mode (which is optional) and all of your characters are Dead, or simultaneously Arrested or Hospitalized, and you have none left, the game is over and you will need to restart from the beginning. “